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Interested in quantifying recognition by T cell receptors binding the same target?

This by @amayer uses the number of (nearly) exactly coincident receptor sequences in a repertoire that are more frequent vs a reference repertoire.

With the right dataset, this can be a very handy approach to interpret antigen-driven T cell selection in #disease.

#immunology #science #Tcell #academia #TCR #math @PNASNews

https://www.pnas.org/doi/10.1073/pnas.2213264120#sec-8