Vertex reports that, over a year after receiving stem-cell therapy, two type 1 diabetes patients no longer need insulin injections and their HgA1c levels declined.
Vertex’s treatment, VX-880, replaces damaged pancreatic islet cells with stem cells that have been “coaxed in a lab to develop into those same insulin producing factories.” 1 of 2 patients dropped out for unstated reasons. Patients do need to take lifelong immunosuppressants.
According to Vertex, 3 additional patients
1/2
(followed only briefly) had a “trajectory. consistent with that observed” in the two patients who are now insulin independent.”
“Cautious optimism,” says Edwin Gale, emeritus UK professor. By: @jasonmast @stats
https://www.statnews.com/2023/06/23/vertex-diabetes-cell-therapy-insulin/
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