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Myocarditis associated with | nature.com/articles/s41541-024 “Available evidence shows that is associated with an increased risk of , but at a much lower level than the risk associated with COVID-19 infection, reiterating a clear positive benefit/risk ratio for COVID-19 mRNA vaccines. To date no definite mechanism for vaccine associated myocarditis has been identified”

NatureMyocarditis associated with COVID-19 vaccination - npj VaccinesFollowing the start of the COVID-19 vaccination campaign, the adverse events of myocarditis and pericarditis were linked mainly to mRNA COVID-19 vaccines by the regulatory authorities worldwide. COVID-19 vaccines have been administered to several million people and the risk of myocarditis post COVID-19 vaccination has been characterised in great detail. At the present time the research data available are scarce and there is still no clear understanding of the biological mechanism/s responsible for this disease. This manuscript provides a concise overview of the epidemiology of myocarditis and the most prominent mechanistic insights in the pathophysiology of the disease. Most importantly it underscores the needed next steps in the research agenda required to characterize the pathophysiology of this disease post-COVID-19 vaccination. Finally, it shares our perspectives and considerations for public health.