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@Anaes_Journal@med-mastodon.comThis study found that in patients with measured peri-op renal parameters, for every 100 elective major non-cardiac surgery procedures, postoperative AKI could be expected to happen in a minimum of four and a maximum of 15 cases.
Almost totally preventable via Narsoplimab or L-fucose bolus, both of which temporarily disable the Lectin Pathway of Complement.
PubMedl-Fucose prevention of renal ischaemia/reperfusion injury in Mice - PubMedIn a recent study, we identified a fucosylated damage-associated ligand exposed by ischemia on renal tubule epithelial cells, which after recognition by collectin-11 (CL-11 or collectin kidney 1 (CL-K1)), initiates complement activation and acute kidney injury. We exploited the ability to increase t …